Chemistry Colloquium: Dr. Joseph Clark

The Department of Chemistry in the College of Arts and Sciences is pleased to welcome Dr. Joseph Clark, an Assistant Professor at Marquette University.

Abstract:

“Precision Labeling of Small Molecules”

Despite the tremendous utility that precisely deuterated small molecules have in chemical research and the development of new medicines, methods to selectively incorporate deuterium into molecular scaffolds are lagging. Not only is highly selective deuteration challenging, but spectroscopic techniques to support advances in selective deuteration reaction discovery are sometimes inadequate. Catalytic transfer deuteration and hydrodeuteration reactions are uniquely equipped to precisely install deuterium into small molecules. New copper-catalyzed reactions for the selective transfer deuteration and hydrodeuteration of alkene and alkynecontaining small molecules will be discussed along with novel spectroscopic techniques for the analysis of isotopic products.