Science and Mathematics
Chemistry Colloquium: Dr. Matthew Eddy
October 8, 2024 at 3:30pm – 4:30pm EDT
Center for Science and Technology (CST), 1-019
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The Department of Chemistry in the College of Arts and Sciences is pleased to welcome Dr. Matthew Eddy, an assistant professor at the University of Florida.
Title: The Influence of Membrane Lipids on GPCR Signaling
Abstract
Membrane lipids are endogenous regulators of G protein-coupled receptor (GPCR) signaling but the structural mechanisms of their influence are not understood. We utilize an integrative biophysical and structural biology approach to investigate how membrane phospholipids and sterols control the conformational equilibria of GPCRs a magnitude comparable to or greater than the influence of bound drugs. Integrating NMR data with correlative functional assays and molecular modeling allows us to propose a molecular mechanism explaining how lipids influence the formation of GPCR signaling complexes.
This event was published on October 1, 2024.
Event Details
- Category
- Science and Mathematics
- Region
- New York Campus
- Open to
- Current Students,
- Faculty
- Organizer
- CAS-Department of Chemistry
- Contact
- Cheryl Lowery
calowery@syr.edu
315.443.2925
- Accessibility
- Contact Cheryl Lowery to request accommodations